Abstract Issue

Volume 12 Issue 3 ( July-September ) 2023

Original Articles

Evaluation of electrocardiographic changes in patients with cirrhosis and their correlation with severity of disease
Dr. Hardip Singh, Dr. Shubham Panwar, Dr. Rakesh Arora

Background: Cirrhotic cardiomyo pathy (CCM) is a distinct heart condition closely associated with liver damage. It involves impaired ventricular function, prolonged ventricular depolarization, and an inadequate response to stress. The study aimed to examine the prevalence of electrocardiographic (ECG) changes in cirrhotic patients and explore their potential correlation with liver disease severity, as evaluated by Child Turcotte Pugh (CTP) class and model for end-stage liver disease (MELD) scores. Methods: This cross-sectional study was conducted on 50 patients of liver cirrhosis (compensated and decompensated), who attended emergency/outpatient services of Guru Nanak Dev Hospital, Amritsar. Electrocardiography findings were assessed using a 12 lead ECG. Compar isons between groups was performed using student t test for continuous variables and chi square and ANOVA test for categorical variables. Pearson’s coefficient of correlation (r value) is used to assess the correlation between two variables. Results: Seventy two percent patients had sinus tachycardia, 74% had QTc prolongation, 34% had low voltage QRS. Only 2 patients had normal ECG while all others had some ECG changes. The heart rate and QTc interval, increased progressively with increasing CTP class (P<0.001) and low voltage QRS and increased QTc correlated positively with increasing MELD scores (P<0.05). Conclusion: Our results show that QTc prolongation and low voltage QRS are significantly related to liver cirrhosis severity as assessed by its relation with CTP and MELD score and that these ECG changes are present in higher frequency in patients having complications of decompensated liver cirrhosis like ascites and hepatic encephalopathy. Keywords: Cirrhosis, Electrocardiography, Cirrhotic cardiomyopathy.

 
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