Introduction: Ovarian cancer is the fifth most common malignancy among women and second most common gynecologic malignancy.1 It is the most common cause of death due to malignancy of female genital tract. In India; the ovary is next in importance to cervix as the seat of cancer of female genital tract. In normal ovulatory cycles, repeated ovulatory rupture and repair can lead to gene mutations3 which can give rise to malignancy. Materials & Methods: Hospital based descriptive study conducted in pathology department of Asian Institute of Gastroenterology, Telangana during the period of January 2022 to December 2022.Purposive sampling technique is used as all the specimens sent for Histo-Pathological examination were studied. Conclusion: Surface Epithelial ovarian tumors is the most common category of ovarian tumors followed by Germ cell tumors, Sex cord stromal tumors in decreasing order of frequency. Incidence of Benign tumors is much higher than malignant tumors with Benign Serous cystadenoma being the most common benign tumor and serous cystadenocarcinoma being the most common malignant tumor. Keywords: Immunohistochemical markers (IHC), Neoplastic Lesions, Non-Neoplastic lesion, Ovarian Tumors