Abstract Issue

Volume 12 Issue 3 ( July-September ) 2023

Original Articles

Assessment of Carotid Artery Intima Media Thickness and Its Correlation to Atherosclerotic Risk Factors in Type 2 Diabetes Mellitus: An Observational Study
Dr. Aditi Rajan, Dr. Anurag Prasad, Dr. A K Agarwal, Dr. V P S Punia, Dr. Ajoy Deshmukh

Background: One of the important causes of mortality in diabetes mellitus (DM) is cardiovascular diseases. Carotid artery intima media thickness (CIMT) is endorsed by the American Heart Association as being safe, non-invasive and less costly method of evaluating sub-clinical atherosclerosis. The main aim was to assess CIMT and its correlation with atherosclerotic risk factors in type 2 DM. Methods: The study was conducted on 100 patients who were adults of >30 years of either gender with diagnosed type 2 diabetes mellitus, admitted in the in-patient department. CIMT was measured with Philips Epiq 7G ultrasound machine having high frequency (3 to 12 MHz) linear transducer. Results: Mean age of enrolled patients was 57.41+8.1 years, 62% being males. 17 patients were found to have atheroembolic disease. Mean CIMT was found to be 0.72+0.21 mm. 30 patients were found to have high CIMT (>0.9 mm). Mean body mass index and mean waist circumference were significantly greater in the high-CIMT group (p<0.05).Mean HbA1c as well as mean post-prandial blood sugar were significantly higher in high-CIMT subgroup (p<0.05).The mean creatinine and lipid parameters were also significantly higher in the high-CIMT group (p<0.05).43.33% patients in high-CIMT group and only 5.71% patients in low-CIMT had athero-embolic evidence. Conclusion: Large number of type 2 DM patients had high CIMT. Additionally, patients with high CIMT were found to have significantly greater presence of atherosclerotic risk factors, indicating that CIMT is a strong indicator for atherosclerosis.

 
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