Abstract Issue

Volume 12 Issue 3 ( July-September ) 2023

Original Articles

Comparison of efficacy of Narrow-Versus Broad-Spectrum Antibiotics in elderly patients with acute exacerbations of chronic obstructive pulmonary disease
Dr. Sanjeev Anand, Dr. Sanjay Singh, Dr. Rishi Yadav

Background: To compare efficacy of narrow-versus broad spectrum antibiotics in patients aged more than 65 years with AECOPD. Materials & Methods: A total of 100 subjects were enrolled. The study focused on subjects aged 65 and above who were hospitalized for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and received a minimum of 48 hours of antibiotic treatment. The data was collected and result was analysed using SPSS software. Results: The study involved a total of 100 patients, with 50 individuals assigned to the narrow-spectrum group and another 50 individuals assigned to the broad-spectrum group. The primary combined outcome was observed in 17 patients (34%) from the narrow-spectrum group and in 22 patients (44%) from the broad-spectrum group, showing no significant difference (P = 0.2). Conclusion: The primary outcome among hospitalized individuals aged 65 years and older with AECOPD who were treated with either broad-spectrum or narrow-spectrum antibiotics.

 
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