Introduction Sudden onset chest pain is one of the commonest causes for presentation to the hospital casualty. Even though acute onset chest pain is very often assumed to be acute coronary syndrome (ACS), after further workup only 15% to 25% of patients with acute chest pain have MI. Aims & Objectives: To determine the frequency of raised serum Gamma Glutamyl Transferase levels in cases presenting with acute coronary syndromes. To determine the possible association between raised serum GGT levels and different subsets of ACS. Materials And Methods: patients admitted with an episode of Acute Coronary Syndrome in the intensive coronary care unit. History of any alcohol intake Surgical conditions causing obstructive jaundice. Results: Out of 150 study population 92 patients were male and 58 were female 40 out of 92 males had a positive value for GGT (43.5%). 34 out of 58 females were positive for GGT (58.6%). The p value was .07. There was no significant correlation between gender and GGT.