Background: Patients with diabetes, along with macro- and microvascular complications, may experience various musculoskeletal disorders such as osteoporosis, osteopenia, diabetic foot syndrome, and Charcot’s arthropathy. The present study was conducted to assess frequency of osteoporosis in post menopausal diabetic women. Materials & Methods: The present descriptive cross-sectional study was carried out over a period a period of 6 months to assess the frequency of Osteoporosis in Post menopausal diabetic women. A semistructured questionnaire was used to find out the sociodemographic background of the patients. The BMD score was determined.Statistical analysis was carried out by using the statistical package for social sciences version 22.0 for Windows (SPSS Inc, Chicago, Illinois, USA). Results: Out of 80 participants, most of the participants were below 60 years of age group(56.25%), and 30% belonged to the 61-70 year age group. The Majority (61.25%) of participant’s age of onset of menopause was 46- 50 years. Osteoporosis of at least one site was present among 81.25% of participants. Osteoporosis of the lumbar spine and femoral neck were present among 71.25% and 53.75% of respondents, respectively. The Majority of participants had Osteoporosis. Conclusion: The present study showed that majority of participants had osteoporosis of at least one site therefore, it can be concluded that postmenopausal women are susceptible to Osteoporosis.