Abstract Issue

Volume 12 Issue 3 ( July-September ) 2023

Original Articles

A study on circulating Plasma Lipid Peroxide and Blood Lead Level in Battery workers in Dehradun District of Uttarakhand
Chandra Shekhar Sharma, Rajeev Singh Kushwaha, Tariq Masood

Aim: A study on circulating Plasma Lipid Peroxide and Blood Lead Level in Battery workers in Dehradun District of Uttarakhand. Material and methods: A total no of 150 subjects (100 battery workers and 50 controls) was participated in the study. Blood samples was collected from the participants by aseptic technique. 5ml blood will be collected and will quickly transferred to test tubes already containing EDTA anticoagulant or plane vials. Blood lead level estimated by lead care blood lead analyzer. The lipid per oxidation was estimated by the method of Okhawa et. al. by measuring the malondialdehyde (MDA) level. Results: The mean age of the study group and control group was 42.85±5.85 and 41.85±4.66, respectively. The mean duration of exposure in the study group was 12.52±2.58 years. Individuals who were consistently exposed to lead had significantly greater amounts of lead in their blood compared to the control group that was not exposed to lead, with mean values of 14.25±2.52 mg/dL and 2.01±0.33 mg/dL, respectively (p < 0.001). In the study group, the average concentration of Plasma Lipid Peroxide was found to be 23.52±4.85 mg/L, whereas in the control group, it was seen to be 10.25±2.87 mg/L. Conclusion: There was a statistically significant positive association seen between blood lead levels and both age and length of exposure in both groups. However, no link was found between blood lead levels and related Plasma Lipid Peroxide.

 
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