Abstract Issue

Volume 12 Issue 2 ( April- June) 2023

Original Articles

To estimate the prevalence, pattern, risk factors, distribution of various congenital malformations and to compare various methods of pregnancy termination
Shivani Sharma, Ankit Prabhakar, Amrita Gaurav

Background: Estimation of prevalence, pattern, risk factors, distribution of various congenital malformations and to compare various methods of pregnancy termination. Materials & methods: A total of 500 subjects were enrolled. Complete demographic and clinical details of all the subjects was recorded. Inclusion criteria for the present study included Antenatal women with congenital anomalies to the foetus registered or referred to department of OBG. Collection of data was done which included age, parity, gestational age, consanguinity, recurrent abortions, maternal infections, folic acid intake, obesity, history of previous anomalies, family history of congenital anomalies, any medical disorders such as diabetes, thyroid diseases. All the results were recorded in Microsoft excel sheet followed by statistical analysis. Results: Overall, congenital malformation was present in 2.2 percent of the cases. Majority of the malformations were detected in second trimester. BMI more than 25 Kg/m2, Overt diabetes, Gestational DM, Thyroid dysfunction, Family history of congenital malformation and History of maternal infection were the risk factors seen in 90.91 percent, 27.27 percent, 18.18 percent, 45.45 percent, 36.36 percent and 27.27 percent of the patients. Methods of termination among cases with presence of congenital malformation was Medical (Mifepristone + Misoprostol), Mifepristone alone, Misoprostol alone, Hysterotomy and Mechanical dilatation with Foley’s Catheter in 54.55 percent, 9.09 percent, 9.09 percent, 18.18 percent and 9.09 percent of the patients respectively. Conclusion: Morbidity due to congenital anomalies can be minimised but not totally preventable by early diagnosis.

 
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