Aim: To evaluate the cases of cervical myeloradiculopathy due to ossified posterior longitudinal ligament (OPLL), different surgical approaches and their outcome. Material and Methods: The present prospective observational analytical study was conducted at Department of Neurosurgery, Bangur Institute of Neurosciences, Kolkata among 54 patients aged over 20 and up to 65 years including both male and female presenting for ossified posterior longitudinal ligament with cervical myeloradiculopathy and underwent surgery for the same from 1st March 2020 to 31stApril 2022.Anterior cervical corpectomy and fusion was done in patients with cervical OPLL involving ≤ 3 levels, massive OPLL involving > 50% of spinal canal and with presence of cervical lordosis and subluxation. Posterior approach by laminectomy was done in patients with multilevel OPLL involving > 3 levels and with OPLL involving <50% of spinal canal. Laminectomy & fusion was done in patients with multilevel OPLL involving >3 levels, without pre-existing cervical lordosis and subluxation, to achieve effective decompression and for maintaining or restoring stability of the cervical spine.All the patients undergoing surgery were followed up at the end of 3 and 6 months to assess the various surgical outcome. Results: Out of these 54 patients 22 patients underwent posterior decompressive laminectomy (B1), 16 patients underwent posterior decompressive laminectomy and lateral mass fusion (B2) and 16 patients underwent anterior corpectomy and fusion (A).The differences of post-operative functional scores and neurological assessment did not reach statistical significance when comparing between the groups. Conclusion: We concluded that all the implemented surgical approaches for cervical OPLL i.e anterior cervical corpectomy and fusion (A), decompressive laminectomy (DL) and laminectomy with lateral mass fusion (LMF) are equally good in terms clinical outcome and effectiveness.