Abstract Issue

Volume 12 Issue 3 ( July-September ) 2023

Original Articles

A prospective study of plasma thromboplastin cell block preparation and conventional smears on serous effusions and its classification based on newly proposed international system for reporting serous fluid cytopathology
Dr. Kamlesh Kumar, Dr. Mamta Dwivedi, Dr. Sneha Chauhan, Dr. Astha Chaudhury, Dr. Veenu Jain

Introduction: Plasma thromoplastincytoblock technique is a simple , cost effective and readily adaptable in routine hospital laboratories as compared to cell block preparations made from conventional techniques such as agar gel or formol alcohol , which is much laborious and time consuming . We applied the recently proposed International system for reporting serous cytopathology (TIS) on the serous effusions and reported our experience. Aim: To study the diagnostic utility of Thromboplastin cell block technique in conjunction with conventional smears and its classification according to TIS. Material and methods: 114 samples were included in the study over a period of 8 months, both conventional and cell block preparations were made. Result: A total of 114 cases were studied: 64 pleural fluid, 45 ascetic fluid and 05 pericardial fluid. 04 (3.5%) were diagnosed as non diagnostic, 69 (61%) as Negative for malignancy, 10 (8.8%) as Atypia of underterminedsignificance, 12 (10.52%) as Suspicious for malignancy, 19 (16.66%) as Malignant. Cellularity and diagnostic yield for malignancy was increased by cell block preparation. Conclusion: Plasma thromoplastin cell block method provides high cellularity, better architectural patterns and a good preservation of nuclear details. TIS is auser friendly reporting system.

 
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