Background: This study was conducted to assess the Combined Surgical and Orthodontic Treatments in Children with OSA. Material and methods: The adenotonsillectomy procedure, along with pre- and post-operative polysomnography, was performed on the children who participated in the study. Before polysomnography and within six months of surgery, caregivers also filled out an OSA-18 quality of life survey. For the purpose of comparing pre- and post-operative scores, student's t-tests were utilized. Results: The study population included 100 children out of which 50 were females and 50 were males. The age of the average person was 8 years. Obesity, asthma, and allergy diseases were the three co-morbidities that occurred most frequently. The average RDI (Respiratory Disturbance Index) prior to surgery was 68.9, but it dropped to 11.3 after surgery (P .0001). Before surgery, patients had a mean total OSA-18 score of 74.98, but after surgery, their scores were 37.53. There was a statistically significant difference between the overall scores and domain scores on the OSA-18 before and after surgery (P .0001). Conclusion: Following one or both of the treatments, there was a significant improvement in the patient's respiratory disturbance index (RDI). However, obstructive sleep apnea may return even after satisfactory treatment has been reported, even after a period of several years. Myofunctional therapy, often known as MT, could be suggested as a follow-up treatment in order to reduce the risk of a relapse. Nevertheless, additional research supported by strong clinical evidence are required to validate these findings.