Abstract Issue

Volume 12 Issue 4 ( October-December ) 2023

Original Articles

Comparative study of serum lipid profile levels in normotensive and hypertensive pregnant women in third trimester of pregnancyand assessment of correlation between blood pressure and lipid profile level among these subjects
Dr. Shaveta Galhotra, Dr. Anubhuti Khare, Dr. Rimjhim Sahu, Dr. Gagandeep Kaur Sidhu, Dr. Vikas Dhawan

Background:Pregnancy-Induced Hypertension Is One Of The Most Prevalent Diseases During Pregnancy That Leads To Maternal And Fetal As Well As Neonatal Morbidity And Mortality All Over The Globe.Hence, The Present Study Was Undertaken With Aim To Measure Serum Lipid Profile In Mild And Severe Hypertensive Pregnancy And To Compare With Normal Pregnancy. Materials And Method: The Present Cross-Sectional Study Was Conducted Among 150 Female Subjects Who Were Divided Into Three Groups With 50 Subjects In Each Group For Assay Of Lipid Profile. Group 1 Comprised Of Healthy Non Pregnant Volunteers As Control. Group 2 Comprised Of Apparently Healthy Pregnant Women In 3rd Trimester Of Pregnancy Having Uncomplicated Pregnancy Without Hypertension.Group 3 Comprised Ofpregnant Women In 3rd Trimester Of Pregnancy Having Pregnancy Induced Hypertension (PIH). Post-Hoc Test And Chi-Square Test Was Used For Analysis With P Value <0.05 Considered As Significant Value. Result:TheMost Significant Increase Was In Levels Of Triglyceride (TG) And Total Choles¬terol (TC). There Was A Positive Correlation Between Blood Pressure (BP) And Triglycerides Level, BP (Systolic) Increased Corresponding TC Value That Increased Significantly (R = 0.333 And P = 0.000). Similarly, BP (Diastolic) Increased Corresponding TC Value That Increased Significantly. (R = 0.281 And P = 0.001). Conclusion:In Hypertensive Pregnant Women, Hyperlipidemia Is More Profound Than In The Normotensive Group. Hence, As A Result We Conclude That Lipids Have An Important Contributory Role In Pre-Eclampsia, And Must Not Be Underestimated During The Hypertensive Diseases Of Pregnancy.

 
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