Abstract Issue

Volume 12 Issue 4 ( October-December ) 2023

Original Articles

Analysis of Different Doses of Clonidine as an Additive to Intrathecal Isobaric Levobupivacaine in Patients Undergoing Infraumbilical Surgeries: An Institutional Based Study
Pankaj Kumar, Gopal Krishan, Dheeraj Saxena

Background: The present study was conducted for comparing different doses of clonidine as an additive to intrathecal isobaric levobupivacaine in Patients Undergoing Infraumbilical Surgeries.Materials &Methods:A total of 60 patients within the age range of 25 to 55 years were enrolled. A total of three study groups were formed with 20 patients in each group as follows: Group 1: Levobupivacaine 0.5% isobaric (3 mL) with normal saline (0.5 mL), Group 2: Levobupivacaine 0.5% isobaric (3 mL) with clonidine 15 μg, & Group 3: Levobupivacaine 0.5% isobaric (3 mL) with clonidine 30 μg. Blood samples were obtained and bassline hemodynamic and biochemical profile was evaluated. During postoperative assessment, Visual Analog Scale (VAS) was used. On a scale of 0 to 10 with 0 indicating no pain and 10 indicating maximum unbearable pain. Rescue analgesia given among patients with VAS Score of more than 3. Continuous monitoring of hemodynamic variables was done intraoperatively and postoperatively. Results:Mean age of the patients of group 1, group 2 and group 3 was 43.8 years, 41.8 years and 45.9 years respectively. Significant results were obtained while comparing the sensory block among the patients of the three study groups.Mean duration of analgesia was significantly higher among the patients of group 3 in comparison to patients of group 2 and group 1.Conclusion:In comparison to 15μg, the addition of 30 μg of clonidine as an adjuvant could safely prolong the duration of postoperative analgesia.

 
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