Abstract Issue

Volume 11 Issue 3 (July-September) 2022

Original Articles

Clinical presentation of patients with AKI and liver cirrhosis
Dr. Mansi Bansal

Background:Hospitalized patients with cirrhosis of the liver frequently experience acute kidney damage (AKI), which is highly significant from a clinical and prognosis standpoint and a risk factor for early in-hospital mortality. The present study was conducted to assess clinical features of patients with AKI and liver cirrhosis. Materials & Methods:82 patients with cirrhosis of the liver and AKI of both genderswere divided into three groups- group I was pre-renal azotemia, group II was hepatorenal syndrome, and group III was acute tubular necrosis. For all patients, Child- Pugh score scores, etiology and creatinine level etc. was recorded. Results: Group I had 14 males and 10 females, group II had 27 males and 13 females and group III had 11 males and 9 females. The etiology for cirrhosis was alcohol in 11, 23 and 8, Hepatitis B in 6, 10 and 5, Hepatitis C in 4, 3 and 4, and cryptogenic in 3, 4 and 3 patients. AKI stage1 was seen in 12, 24 and 11, stage 2 in 8, 10 and 6 and stage 3 in 4, 6 and 3 patients in group I, II and III respectively. The difference was significant (P< 0.05). The mean Child- Pugh score was 10.3, 10.5 and 11.6. The Max creatinine level was 3.7 mg/dL, 4.6mg/dL and 4.2 mg/dL. eGFR at admission (mL/min/1.73 m2) was 38.2,26.2 and 35.2. Hospital stay was 12.3 days, 10.6 days and 11.1 days in group I, II and III respectively. The difference was non- significant (P>0.05). Conclusion: Acute renal damage in patients with liver cirrhosis is linked to a high death rate while hospitalized. Child-Pugh scores may be considered as indicators of AKI.

 
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