Introduction: This study was carried out to assess the magnitude and clinical patterns of pyodermas, their causative micro-organisms, and the antibiotic susceptibility patterns. Materials and Methods: All cases of primary and secondary pyodermas in age group <15 years were included. A complete general, systemic, and dermatological examination was done. Relevant investigations, including complete blood count (CBC), urine examination, blood sugar [fasting and postprandial (F/PP)] in all cases and investigations like Human immunodeficiency virus (HIV) serology, peripheral blood film (PBF), liver function tests (LFTs), renal function tests (RFTs), and thyroid profile as and when indicated, were carried out. All these findings were recorded in a pro forma. Results: On categorisation of different pyodermas, primary pyodermas (58.4%) were more prevalent than secondary pyodermas (38.6%). Out of the primary pyodermas, impetigo was the most common (23.3%) followed by furunculosis (11.1%). Infected scabies (14.9%) was most frequently encountered cause of secondary pyoderma followed by infected atopic dermatitis (9.2%). Conclusion: Most of the bacterial strains were found to be resistant to one or more antibiotics. With knowledge of the likely causative organisms and their resistance patterns, the most suitable antibiotic therapy can be started without waiting for anti biogram results, and thus help avoid unnecessary medication with ineffective drugs.