Abstract Issue

Volume 13 Issue 3 (March) 2024

Original Articles

Prevalence, Risk Factors Profile And Treatment Outcomes Of Coronary Slow Flow Phenomenon In Angiographically Normal Coronary Arteries
Dr. Renubala

Background: Coronary slow flow (CSF) is an angiographic diagnostic finding characterized by delayed opacification of epicardial coronary arteries by slow progression of contrast agents in the coronary tree in the absence of coronary artery obstruction.The prevalence & risk factor profile is not well documented in CSF ,hence we intend to study prevalence, risk factors profile and treatment outcomes of CSF phenomenon in angiographically normal coronary arteries. Materials and Methods: Allpatients who underwent coronary angiography between January 2018 and October 2018 in our center were evaluated for inclusion in this study. Consecutive patients with coronary slow flow phenomenon and similar no of consecutive controls with normal coronary flow were evaluated. Demographic variables, information on the traditional CAD risk factors and hema¬tologic parameters were obtained before angiography. All patients with slow flow phenomenon got their treadmill exercise testing done before discharge and at follow up after 1 month with emphasis on exercise time, ST segment changes and duke treadmill score (DTS). Results: During study period, out of 5192 coronary angiograms performed in our institution, 511 patients with normal epicardial coronaries and 56 patients with coronary slow flow phenomenon as per our study protocol (i.e. 1.1% of all coronary angiograms and 10.96 % of normal coronary angiograms). CSF was more common in the males 44 (78.6 %) than female 12 (21.4%).Among patients with CSF most common presentation was CSA (39.3%) followed by USA( 33.9 %), NSTEMI (19.6 %), STEMI (3.6%) and atypical chest pain (3.6%) . Depression, oral tobacco and smoking were significantly more common in case group than control group amongst clinical characteristics. Coronary slow flow was seen in all three vessels in 30(53.6 %) patients, LAD in 21 (37.5%) patients, RCA in (7.1%) and LCX in (1.8 %), patients out of 56 patients. In patients on Nicorandiland Diltiazem there was significant changes observed on exercise time and duke treadmill score, while there were no significant changes observed in pts on nitrates or statins. Conclusion: Prevalence of CSF phenomenon was 1.1 % of all coronary angiograms and 10.96% of normal coronary angiograms. Gender, Depression, oral tobacco chewing and smoking had a significant and independent positive association with CSF phenomenon. In our study there was a significant improvement in functional status of patients nicorandil and Diltiazem which was not observed in pts on nitrates or statins.

 
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