Background:Influenza and parainfluenza viruses are respiratory pathogens that can cause severe illness, especially in children. Influenza viruses, particularly influenza A and B, are a common cause of respiratory illness in children, especially during the flu season. The present study was conducted to assess outcome of influenza and parainfluenza associated pediatric ICU admissions. Materials & Methods:72 children infected with influenza and parainfluenza infection of both gendersadmitted to ICU. The respiratory viruses were identified using conventional diagnostic methods, including direct immunofluorescence testing (DIFT) on respiratory samples (e.g. nasopharyngeal aspirates–NPAs; bronchoalveolar lavages–BALs, tracheal aspirates–TAs, and oral swabs), with confirmation and typing by type-specific DIFT. Results: Out of 72 patients, males were 42 and females were 30. There were 38 cases of influenza and 34 cases of parainfluenza infection. Bacterial co- infection was seen among 12 and 7, ventilation was required in 12 and 7, systemic antibiotics in 38 and 32, systemic corticosteroids were given in 8 and 10 cases, the mean PICU stay was 3.1 days and 3.4 days. There were 2 mortalities in influenza and 1 in parainfluenza cases. The difference was non- significant (P> 0.05). Conclusion: Important childhood morbidity and PICU admissions may be linked to the pandemic H1N1, influenza, and parainfluenza viruses.