Aim: A Comparative study to assess perceived stress and coping among BSc nursing students regarding annual and semester examination system, at selected nursing colleges, Punjab. Materials and methods: A cross-sectional descriptive research was undertaken on Bachelor of Science in Nursing students from Punjab. The online questionnaire has three sections: sociodemographic data, a modified perceived stress scale, and a modified brief coping strategies scale. Participants were granted consent and informed of the study's objective via an online survey questionnaire. The questionnaire was self-administered and included socio-demographic information, the Perceived Stress Scale, and the Brief Coping Strategies Scale. The participants were given an email address to express their views or correspond with the writers. Participants who choose not to complete the questionnaire for personal reasons were allowed to withdraw from the research. Data was collected from a sample of 200 students. Results: The stress levels of students, with a mean of 34.62±3.64 for the semester and 29.12±2.74 for the yearlong period. The level of stress experienced by students throughout the semester and annual examinations varies. Mild stress was reported by 5 students during the semester and 4 students during the annual exams. Moderate stress was reported by 50 students during the semester and 85 students during the annual exams. Severe stress was reported by 45 students during the semester and 11 students during the annual exams. The Coping scores of students under the semester and yearly test systems. The Low scores are 7 and 11, the Moderate scores are 77 and 84, and the High scores are 16 and 5. Conclusion: Our research determined that evaluating the stress levels of students during test preparation was a useful method to identify variables associated with exam-related stress. Hence, it would be advantageous to familiarize oneself with the first indications of stress and techniques to manage exam-related stress.