Abstract Issue

Volume 12 Issue 2 ( April- June) 2023

Original Articles

Correlation of 5 independent markers of metabolic syndrome in psoriasis patients: a case control study
Dr. Pallavi Phadnis, Dr. Meenakshi Tandon, Dr. Shyam Govind Rathoriya, Dr. Rochit Singhal, Dr. Vivek Choudhary

Background: Psoriasis is a persistent inflammatory condition that affects skin as well as other parts of the body. Psoriasis has been linked to metabolic syndrome in previously conducted studies and has been the subject of its own fair share of research. Aim: Correlation of 5 independent markers of metabolic syndrome with psoriasis patients. Material and methods: A total of 200 people who had clinically confirmed psoriasis as well as 200 people who did not have psoriasis but attended the outpatient dermatology department, were involved in the study. Individuals who were not receiving any systemic medicines at the time of the trial and who did not have hyperglycemia, a disordered lipid profile, or hypertension were chosen for the research.Blood pressure, body mass index, waist circumference, fasting lipid profile, and blood sugar were assessed in all subjects. Results: There were 200 individuals diagnosed with psoriasis.Metabolic syndrome was significantly more common in psoriatic patients than in controls (57% vs. 17.33%, P = 0.00001).Psoriatic patients had higher prevalence of raised fasting blood sugar (46.5% vs. 17.5%, P =0.00001 ), hypertriglyceridemia (34% vs. 24%, P = 0.0275), low high-density lipoprotein (55.5% vs. 19%,P = 0.00001), and hypertension (21% vs. 12%, P = 0.0153). Hence a temporal association was found between the psoriasis and individual components of metabolic syndrome. Conclusion: The present study concluded psoriatics having chronic course have a temporal association with the metabolic syndrome and a substantially greater incidence of its components.

 
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