Abstract Issue

Volume 12 Issue 2 ( April- June) 2023

Original Articles

A study on the anaesthetic and analgesic effects of intravenous dexmedetomidine as premedication for spinal Anaesthesia
Dr. Ayushi Ramawat, Dr. Sameer Goyal, Dr. Sonu, Dr. Prakash Chandra Audichya, Dr. Vijay Kumar, Dr. Krishan Gopal Jangir

Background: Spinal anaesthesia is a popular technique for infraumblical surgeries. Dexmedetomidine is a highly potent novel α2-adrenoceptor agonist also used as adjunct in spinal anaesthesia. Aim and Objectives: The aim of the present study is to assess the effects of intravenous Dexmedetomidine as premedication on the onset, level and duration of sensory and motor blockade, analgesia and sedation in patients undergoing infraumblical surgeries under Bupivacaine (hyperbaric, 0.5%, 3mL) spinal anaesthesia. Material and Methods: A total of 100 patients undergoing spinal anaesthesia were randomly divided into two groups, Group D (n=50) received inj. Dexmedetomidine 0.5mcg/kg diluted in 10ml of sterile water and Group C (n=50) received 10ml of normal saline intravenously over 10 mins half an hour before surgery. Result: The sensory block duration was significantly higher in group D (137.6) than in group C (74.2), p=0.000, and the motor block in group D (178) was significantly higher as well than that in group C (129.6), p=0.000. The time of request for rescue analgesia in the postoperative period was significantly extended in group D (236.24±45.91) when compared to group C (145.80±22.50), p=0.000. The Ramsay sedation score of the patients in group D was significantly high-82% of the patients had a sedation score of 3 whereas all the patients in group C had Ramsay sedation score of 2 only. Conclusion: We concluded that the use of intravenous Dexmedetomidine as premedication prolonged the duration of sensory and motor block while maintaining a stable hemodynamic profile and providing adequate arousable sedation.

 
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