Abstract Issue

Volume 12 Issue 3 ( July-September ) 2023

Original Articles

A prospective study on maternal and fetal outcome in pregnancy with hepatobiliary disorders
Dr. Reshma, Dr. Anita Madan, Dr. Jagdeep Kaur

Background: According to the literature, a mortality rate of 0-25% has been reported among mothers with pregnancy-related liver diseases. The aim of this present study was to identify the various etiologies and distribution of hepatobiliary disorders in Pregnant women attending a tertiary care centre in Punjab with reference to age, parity and trimesters, and also to determine the feto-maternal outcome. Materials and method: This Study was conducted Prospectively in the Department of Obstetrics and Gynaecology, Government. Medical College, Amritsar for the pregnant women with liver disease attending the indoor and outdoor services (Between January 2020 to May 2021). Patients were subjected for routine investigations to detect liver abnormalities. Based on inclusion and exclusion criterias 245 pregnant women with liver disease in pregnancy were followed from time of admission till 6 weeks postpartum period to know their maternal and fetal outcome, complications and prognosis associated with these liver disorders. Results: Out of 245 subjects, 37.1% were from urban areas and 62.9% belong from rural background. 37.5% were diagnosed with intrahepatic cholestasis of pregnancy, followed by 28.2% with Preeclampsia, 20.4% had Eclampsia. Raised blood pressure was observed in 2nd Trimester of pregnancy in 22% of the cases whereas 55.9% pregnant females had raised blood pressure in the 3rd trimester. In 17.1% pregnant females icterus was present, while in 31% pregnant females pallor was present. In fetal outcome 86.1% babies born were alive and 13.9% were still birth. Intrauterine fetal growth restriction was noted in 37.1% cases. Out of total of 211 live births, 26% (55) did not present with any post natal complication, while 15.6% babies were admitted to SNCU, 1.42% admitted to NICU, 4.73% had sepsis as a complication, 31.27% had neonatal Jaundice, 14.2% had respiratory distress syndrome, 2.36% had metabolic complications and 4.26% had neonatal death. Conclusion: There is paucity of data in literature regarding predictors of adverse maternal outcome in Pregnancy with hepatobiliary disorders. Further studies are required to assess whether pregnancy can be prolonged in cases of infective hepatitis in order to improve the perinatal outcome. More studies with a larger sample size is recommended. Key words: Hepatobiliary, Pregnancy.

 
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