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Volume 12 Issue 3 ( July-September ) 2023

Original Articles

A clinical study of efficacy of limbal stem cell transplantation in the management of pterygium
Dr .Venumadhav Mothukuri, Dr Chandra Bhanu Karamthoth Bhukya, Dr Haridev Kumar Koochan, Dr. Shanti Kumar Goparaju

Background: Pterygium is a fairly common ocular condition. It appears as a triangular fold of vascularised conjunctiva drawn on to cornea, apex of which is towards the cornea and the base spreads out and merges with the subconjunctival tissue The prevalence of pterygium varies from 1 to 15% depending on the geographical location of the population under analysis Although in the early stage the condition is symptomless, bothering some patients cosmetically but in later stage, it may cause impairment of vision due to two reasons , one by covering the pupillary area of the cornea and second by altering the curvature of cornea due to fibrosis, with resulting astigmatism. For management of this condition surgery in the form of excision is done Although surgery is claimed to be fairly effective treatment, no surgical technique is universally accepted. Recently it is proposed that limbal epithelial stem cells control corneal epithelial health. Limbal stem cell deficiency as one of the important cause for pterygium has been proved and use of limbal stem cells as a surgical technique for prevention of recurrence of pterygium and management is ubiquitous This study concerns with a clinical study of pterygium excision with limbal stem cell transplantation. StudyDesign: The study designis of case series. Aim of the Study: To study the efficacy of limbal stem cell transplantation in the management of pterygium and to evaluate the postoperative outcome & recurrence rate after removal of pterygium combined with limbal stem cell transplantation. Results: The present study is an analysis of 50 pat ients wi thprogressive pterygium of more than 2mm needing surgical intervent ion; done in the Depar tment of Ophthalmology, Regional Eye Hospital,Warangal, Telangana, between December Conclusion: 1. Pterygium excision with limbal stem cell transplantation has low recurrence rates 2. There is lower incidence of serious complications. 3. Patients have good cosmetic results. Thus, pterygium excision with limbal stem cell transplantation might finally provide the solution for the effective management of pterygium.

 
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