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Volume 12 Issue 3 ( July-September ) 2023

Original Articles

Assessment of C-reactive protein (high sensitivity) in cases of allergic rhinitis: A cross sectional study
Dr. Shashank Tyagi, Dr. Hansraj Maurya, Dr. Amit Jain, Dr. Hemant Kumar Jain

Background & Objectives: Allergic rhinitis is a prevalent chronic respiratory disease. C-reactive protein (CRP) serves as a marker for inflammation and infection. Previous research has demonstrated a positive correlation between elevated CRP levels in allergic rhinitis and asthma. This study aimed to assess high sensitivity CRP levels in cases of allergic rhinitis and in healthy controls. Materials and Methods: The study included 60 male and female subjects between the ages of 18 and 40 years. Among them, 30 males and females diagnosed with allergic rhinitis, attending the Ear, Nose, and Throat Outpatient Department of a tertiary care hospital in Central India were selected as cases. Additionally, 30 healthy male and female individuals were chosen as controls, following careful adherence to inclusion and exclusion criteria. CRP levels were measured using a latex-enhanced turbidimetric immunoassay (CRP kit). Results: The study revealed significantly higher CRP levels in cases of allergic rhinitis when compared to the controls (P < 0.05). Conclusion: The findings of this study indicate that allergic rhinitis cases have increased CRP concentrations compared to the controls. The observed elevation in CRP levels can be attributed to airway inflammation associated with allergic rhinitis.

 
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