Background: Inadequate research has led to the misdiagnosis of benign lesions as malignant, necessitating unnecessary surgery. In order to meet the challenges presented to the surgical pathologist when diagnosing a bone tumor, a standard approach to the radiographic examination, clinical history, and histopathology is necessary. Objective: The purpose of this research is to better characterize bone tumors by comparing the histopathological diagnosis and radiological evaluation of the tumor. Study Design and Methods: This is a prospective study on patients who were referred from the Orthopaedics Department to the Department of Radio-Diagnosis and Pathology with pain and swelling. In order to assess patients, conventional radiographs and MRIs were used. The results were then classified as benign or malignant bone tumors, whenever possible, by comparing them to histopathological findings. Histopathological testing was performed on the tissues from the afflicted regions. Results: A total of 40 patients, ranging in age from 20 to 70, were examined. Males predominated at the highest tumorincidence, which occurred between 51 and 60 years of age. The majority of tumours (60%) were benign rather than malignant. With radiological imaging, Ewing's sarcoma was a big malignant tumour and osteoid osteoma was a major benign tumour. According to histological analysis, Ewing's sarcoma was the predominant malignant tumour and osteoma and osteoid osteoma were the major benign tumours. Only 13 out of 40 cases in which the association of bone tumours based on radiological and histological evidence was incorrect. Conclusions: Radiology classifies the lesion type accurately, despite the possibility that it may not do so for all histopathological subtypes of the bone tumor. Though radiology may not give the exact histological variant of the bone tumour, it accurately indicates the nature of the lesion and clinicians should always investigate bone biopsy.