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Volume 12 Issue 4 ( October-December ) 2023

Original Articles

To conduct a morphological examination of bone marrow aspiration cytology and establish its clinical correlate
Dr. Abhishek Gupta, Dr. Zia Ur Rehman Khan

Aim: To conduct a morphological examination of bone marrow aspiration cytology and establish its clinical correlate. Materials and methods: The procedure of marrow aspiration was conducted inside the pathology department, with the posterior iliac spine being selected as the preferred location for the procedure. In a limited number of individuals, the sternum was also used for aspiration. Leishman's stain was used to stain all of the slides, and in some instances, additional stains were added as needed. A limited number of uncontaminated slides and aspirate samples were examined for the purpose of immunophenotyping and cytogenetic analysis. Results: Among the total sample size of 276 individuals, 166 were identified as male, while 110 were identified as female. The examination conducted by the researcher revealed the presence of bicytopenia, leading to a diagnosis of iron deficiency anaemia (IDA). The predominant observation in the general examination was pallor, which was then followed by the presence of splenomegaly. The primary reasons for bone marrow aspiration (BMA), with pancytopenia being the most prevalent indication (29.3%). This is followed by unexplained fever, accounting for 13.8% of cases, and probable leukaemia, accounting for 11.2% of cases. The predominant diagnostic seen was deficiency anaemia, accounting for 31.9% of the total cases. Conclusion: The BMA procedure has significant value as a haematological diagnostic tool. The use of diagnostic, prognostic, and therapeutic assessment in a range of haematological and nonhematological illnesses is beneficial when applied to patients who have undergone thorough clinical evaluation and meticulous analysis of peripheral smear.

 
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