It is critical in the realm of healthcare to ensure the safe and effective usage of pharmaceuticals. Prescription auditing is a significant approach for supporting healthcare facilities, particularly teaching hospitals, in analyzing and improving their pharmaceutical practices. This technique comprises a thorough evaluation of prescription patterns, adherence to physician advice, and overall drug management in a hospital context. Teaching hospitals, as hubs of medical research and instruction, play a critical role in deciding the future of healthcare. Objective: Of this is to evaluate the prescription writing compliance with defined guidelines and accepted standards at a selected teaching hospital and to determine the legibility of the prescriptions. Methods: Was prospective, cross-sectional study conducted on various inpatient and outpatient prescriptions for three months 2023. The study Results :The conformance of the various parameters with descriptive statistics is above 60 plus percentage out of 700 out patients and in patient’s prescriptions and also study result helped us to strictly monitor and continuous audit to meet the compliance level. Conclusion: All clinicians must be educated on rational prescribing by training, routine exams, monitoring, and providing non-judgmental feedback. Prescription auditing on a regular basis can help enhance prescription quality as well as patient care quality. To help improve prescribing standards and reduce prescription errors needs to adopt a consistent prescription policy.