Objective: This study aimed to measure anterior chamber depth (ACD) and anterior chamber angle (ACA) using optical coherence tomography before and after cataract surgery in glaucoma patients. Methodology: This prospective, cross-sectional study employed purposive sampling and included 25 eyes of patients with primary open-angle glaucoma and grade I & II cataract, as well as 15 eyes of patients with pseudoexfoliation glaucoma. Group A comprised patients with primary open-angle glaucoma and grade II, III cataract, while Group B included patients with secondary glaucoma and grade 2 and 3 cataracts. Results: In Group A, the majority (52.0%) of patients were aged 40-50 years, while in Group B, the majority (53.3%) were aged 51-60 years. The difference in the distribution of studied patients between the groups was statistically insignificant (p > 0.05). The mean ACA pre-operative, post-operative after 1 week, and post-operative after 4 weeks in Group A were 35.93±2.74, 43.33±5.21, and 48.27±5.46, respectively. The differences were statistically insignificant (p > 0.05). Additionally, in Group A, the mean central corneal thickness (CCT) pre-operative, post-operative after 1 week, and post-operative after 4 weeks were 532.80±48.77, 562.12±44.60, and 544.76±42.05, respectively, with statistically insignificant differences (p > 0.05). Conclusion: In eyes with primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PXG), intraocular pressure (IOP) and anterior segment parameters, including ACD, ACA, and CCT, may alter after cataract surgery. These changes may vary between PXG- and POAG-affected eyes.