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Volume 11 Issue 1 (January-March) 2022

Original Articles

Assessment of clinical profile of children with Hepatitis A infection
Dr. Diksha Sharma, Dr. Prachi Jain

Background: Acute Hepatitis A is a viral infection that affects the liver and is caused by the hepatitis A virus (HAV). The present study was conducted to assess the clinical profile of children with Hepatitis A infection. Materials & Methods: 56 patients under the age of 15 years attended the department of paediatrics with acute hepatitis of both genderswere subjected to blood tests like complete blood count, liver function tests, prothrombin time and serum ammonia in cases with altered sensorium. Cases were managed conservatively with symptomatic treatment and dietary advice. Results: Age group 0-5 years had 4 males and 6 females, 5-10 years had 7 males and 9 females and 10-15 years had 19 males and 11 female child patients. Clinical features were fever seen in 47, jaundice in 56, abdominal pain in 37, vomiting in 15, dark colored urine in 39, altered sensorium in 21, lethargy in 13 and diarrhoea in 25 patients. The difference was significant (P< 0.05). The normal serum albumin level was 5.8 g/dl, prothrombin time was 13.2 seconds, TLC was 11214.5 cu/mm, total bilirubin was 1.3 mg/dl, conjugated bilirubin was 1.1 mg/dl, alanine transaminase (ALT) was 61.2 U/l, aspartate transaminase (AST) was 65.7 U/l and ammonia was 96.2 mcg/dL. Conclusion: Although hepatitis A is a self-limiting illness, there are a number of risk factors that can make it worse, including poor eating habits, drug use, co-infection, and underlying liver disease. Therefore, every instance needs to be monitored until full recovery.

 
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