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Volume 12 Issue 4 ( October-December ) 2023

Original Articles

Exploring the Interplay Between Glycosylated Hemoglobin and Dyslipidemia in Individuals with Type 2 Diabetes Mellitus
Dr. Uttam Chatterjee, Dr. Satya Prakash Gupta, Dr. Rashi Jaiswal, Dr. Goldi Singh, Dr. Varuna

Background: Individuals with both diabetes and concurrent dyslipidemia are frequently vulnerable to cardiovascular disease and increased mortality. Early interventions targeting the normalization of circulating lipids have demonstrated efficacy in reducing cardiovascular morbidity and mortality. Therefore, the objective of this study is to investigate the correlation between dyslipidemia and glycemic status in individuals diagnosed with type 2 diabetes. Methods: This cross-sectional and prospective study spanned a duration of one year, involving a cohort of 140 patients diagnosed with type 2 diabetes (T2DM) and concomitant dyslipidemia. The assessment encompassed the evaluation of various parameters, including fasting blood glucose (FBG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), and glycosylated hemoglobin (HbA1c) levels. Results: The distribution of Glucose Triad results, comprising Fasting Blood Sugar (FBS), Postprandial Blood Sugar (PPBS), and Hemoglobin A1c (HbA1c) levels in patients, is presented as Mean± SD. The mean FBS was 170.48±36.64, mean PPBS was 230.49±94.39, and mean HbA1c was 7.48±0.63. Additionally, the mean total cholesterol was 220.53±16.53, mean total triglyceride was 210.83±20.65, mean HDL was 30.63±3.96, mean LDL was 140.14±7.63, and VLDL was 40.46±3.69. HbA1c exhibited a positive correlation with the mentioned parameters. Conclusion: The findings of the study highlight the utility of HbA1c as an effective marker for lipid profile, suggesting its potential role in screening diabetic patients at a heightened risk of developing cardiovascular diseases.

 
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