Background: Induction of labour is usually performed by administering oxytocin or prostaglandins to the pregnant woman or by manually rupturing the amniotic membranes. The present study was conducted to assess the usage of Misoprostol for induction of labor in full-term pregnancy. Materials & Methods: 80 Primi gravida women were divided into 2 groups of 40 each. Group I was those in which females were induced with 25 μg misoprostol for cervical ripening labour induction and group II with no induction and watched for spontaneous progress of labour. Results: Education was primary in 18 in group I and 14 in group II, high in 20 and 22, degree in 2 and 4 in group I and II respectively. The socioeconomic status was upper in 5 and 7, middle in 11 and 13 and lower in 24 and 20 respectively. Status was booked in 25 and 26 and unbooked in 15 and 14 respectively. Bishop score was 1 in 18 and 8, 2 in 12 and 11, 3 in 3 and 4, 4 in 4 and 5 and 5 in 3 and 2 in group I and II respectively. The difference was non- significant (P> 0.05). Apgar score <7 was seen in 16 and 18 and >7 in 24 and 22. NICU admission was seen in 19 and 17. Perinatal morbidity was MAS was 3 and 1 and RDS in 2 and 3, birth asphyxia in 1 and 9 and meconium-stained liquor in 3 and 5 in group I and II respectively. Maternal complications were PPH seen in 2 and 5, cervical tear in 4 and 8, perineal tear in 2 and 0. The difference was non- significant (P> 0.05). Conclusion: Misoprostol is a useful medication for priming and inducing labor. When spontaneous labor progression is not possible, it can be utilized to induce labor in patients.