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Volume 12 Issue 4 ( October-December ) 2023

Original Articles

Effect of intravenous iron sucrose on blood parameters in pregnant females with moderate anaemia
Aakash Verma, Arpana Singhal, Srishti Kukreja

Background: During pregnancy, anaemia is most often (about 80%) caused by iron deficiency and occasionally by more complex conditions involving deficient production or accelerated destruction of erythrocytes. The aim of this study is to observe rise in haematological parameters and side effects after treatment with iron sucrose. Material and Method: The study included 50 antenatal patients with period of gestation from 32 to 35 weeks having iron deficiency anaemia with haemoglobin levels 7-9 g% and serum ferritin levels less than 12 ng/ml. Intravenous iron sucrose was given in the dose of 100 mg on alternate days, according to the calculated dose. Patients were observed for side effects or anaphylactic reactions. Any minor or major side effects were documented. Results:There was significant increase in the haemoglobin values before and after treatment from 7.2 g/dl (SD-0.76) to 10.12g/dl (SD 0.74) (p value< 0.001).Level of serum ferritin was 23.8 ± 2.4 µg/l before treatment and 31.91± 2.61 µg/l after treatment. mean corpuscular volume (MCV) before treatment (68.1±3.62 fl) and after treatment was (85.64 ± 1.76fl). 90% of the patients had no side effects. Chills and rigor was the most common side effect (4%). Only 1 (2%) case of headache, nausea and thrombophlebitis was seen. Chills and rigor was the most common side effect (4%). Only 1 (2%) case of headache, nausea and thrombophlebitis was seen. Conclusion: Intravenous iron sucrose is as effective in improving haemoglobin, haematocrit values in the treatment of iron deficiency anaemic during pregnancy.

 
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