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Volume 12 Issue 4 ( October-December ) 2023

Original Articles

Thyroid associated ophthalmopathy - A study comparing the clinical profile with hormonal status and orbital imaging
Dr. Pankaj Baruah, Dr. Kashmina Kumar, Dr. Shubham Kaushal

This study aimed to investigate the epidemiological characteristics and clinical course ofOphthalmopathy associated with thyroid dysfunction, focusing on the correlation betweenhormonal status and clinical findings. The inclusion criteria encompassed thyrotoxicosispatients with eye signs, cases with diffuse goiter and eye signs, and cases with eye signslackingevidence ofthyroid dysfunction. Conducted at RIO, GMCH, the study spanned from January to October 2023, involving athorough ocular examination, including history-taking, extraocular examination, exophthalmometry, tonometry, fundus examination, and imaging studies. Follow-ups with the endocrinology department included T3, T4, TSH estimation, and TAB presence assessment. The study drew insights from relevant departments and referenced existing literature, suchas studies by OfiraZloto, AlankritaMuralidhar, Bartley et al, and SagiliVijayaBhaskarReddy. Notable findings included gender differences in thyroid eye disease presentationand prognosis, varying prevalence rates, and bimodal incidence peaks.Symptomdistribution revealed discomfort/pain as the most common (30%), followed by lacrimation/photophobia (27%) and diplopia (20%). Eye involvement distribution indicated bilateralinvolvement in the majority of cases. The conclusion highlighted common occurrencebetween 30-50 years, a male-to-female ratio of 1:4, and ocular discomfort/pain as aprevalent complaint. Raised IOP, proposis, and enlarged extraocular muscles (EOM) werenoted,emphasizing the absence ofa directTH level correlation withTED course. Ultrasonography proved valuable in detecting EOM enlargement without measurableproptosis.

 
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