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Volume 13 Issue 1 (January) 2024

Original Articles

Maternal and Fetal Complications And Outcome Of Pregnancy In Patients Presenting With Threatened Abortion
Dr. Huma Afzal Mirza, Dr. Nigare arzoo, Dr. Meghna Garg

Background: This study was conducted to assess maternal and fetal complications and outcome of pregnancy in patients presenting with threatened abortion. Material and methods: Written informed consent was taken from each participating subject fulfilling the inclusion criteria after explaining the study protocol in details. A detailed history was taken including age, parity, ANC book in g status, present history including amount of vaginal bleeding, number of episodes, association with pain abdomen, aggravating/relieving factors, progesterone supplementation given, past medical, surgical and obstetric history from the patients. Detailed physical examination of each patient was done including weight, general physical examination, systemic examination, abdominal and per-vaginal examination for size of uterus, amount of vaginal bleeding, local causes of bleeding and cervical status was recorded. Data was collected from the routine investigations done for antenatal patients: Blood Group, CBC,HIV, Australia antigen, VDRL test, Glucose Challenge Test, S.TS Hand Urine routine/microscopy. Results: In 61cases with threatened abortion where pregnancy continued beyond 20weeks of gestation, premature rupture of membrane was present in 6 (9.8%) cases, manual removal ofplacenta was done in 3 (4.9%) cases, IUGR was seen in 6 (9.8%), Intrauterine Death in 1(1.6%), still birth in 2 (3.3%) and neonatal death was seen in 2 (3.3%) cases. While in 72controls, where pregnancy continued beyond 20 weeks of gestation premature rupture of membrane was done in 3 (4.2%) controls, IUGR was seen in 3 (4.2%), and still birth in 1(1.4%)controls. In trauterine Death and neonatal death was not observed in any controls. Mean APGAR score at 1 minute and 5 minutes was higher in baby born from women with threatened abortion (6.71±1.72 & 7.64±1.91 respectively) compare with baby of women without threatened abortion (7.21±0.75 & 8.04±1.25 respectively) but it was not statistically significant. Conclusion: Concluding the result of present study, first trimester bleeding can be a predicting factor for late trimester pregnancy outcome; both maternal and foetal outcomes. It is therefore necessary to consider these pregnancies as a high risk group for which antenatal care should be performed carefully. Although the cause cannot be delineated in majority of the cases of threatened abortion, but the role of oxidative stress has been proven by several studies, and the role of antioxidants in the management of threatened abortion can be further evaluated in future studies.

 
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