Introduction: Treatment of breast abscesses is based on incision and drainage and antibiotic therapy against the bacteria causing infection. The aim of this study was to know the bacteriological profile and incidence of breast abscess. Methods:110 Patients with breast pathology had visited to our institution between January 2022 and January 2023. Out of 110 patients, 56 patients were diagnosed with fibroadenoma, 29 patients were malignant breast tumours, 17 patients had mastalgia, whereas only 20 patients were diagnosed with breast abscess on clinical and USG findings. In our study patients with age group 30-60yrs were considered in our study, and patients who had history of smoking, DM, HIV, Malignant tumours, Abscesses secondary to surgical wound infection was in exclusion criteria. The present study was conducted on 20 female patients with provisional diagnosis of breast abscess on clinical basis with an aim to study the bacteriological profilei.e. aerobic and anaerobic bacteria, management of breast abscess and to compare the results of our present study with other relevant studies and to see whether breast abscess is more common in lactating or non - lactating females. Results: Twenty patients were included in our study; In which Staphylococcus aureus was the most frequent agent in lactating women. Anaerobic bacteria were isolated in 4 patients (20%) of abscess cases including (lactating and non-lactating). Whereas in Aerobic bacteria we had 12 patients (60%) lactating and 4 (20%) patients non-lactating.