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Volume 13 Issue 3 (March) 2024

Original Articles

Role of Intralesional Bleomycin Injection in Management of Low Flow Vascular Malformations in Children
Dr. Vishwanath Tripathi

Background:Vascular lesions encompass a wide range of pathologies and are comparatively common in infancy and youth. Material and Methods: This is an observational cohort study conducted in Department of General Surgery, Sarojini Naidu Medical College and Hospital, Agra among all 25 children with radiologically confirmed low flow vascular malformations during the period of one year (January 2018 to December 2019). Multiple sessions of sclerotherapy (Intralesional Bleomycin Injections IBI) were performed. Results: A total of 25 patients were treated with serial intralesionalbleomycin percutaneous injection. Overall, a >50% improvement was seen in 80% of this cohort of patients; 24% of the total cohort demonstrated a complete response. One patient in the venous malformation group only demonstrated a fair response following four treatments, having missed several outpatient appointments and follow-up during the treatment course. Conclusion: Intralesional bleomycinsclero the rapy is a great treatment choice for low-flow VMs. In paediatric patients with symptomatic or disfiguring low flowvascular malformations, serial in tralesional bleomycin in jectionshaveproven to beasafeandeffectivetreatmentoption.

 
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