Background: Hyperglycemia anomalies in the metabolism of proteins, lipids, and carbohydrates characterise diabetes mellitus (DM), a chronic metabolic disorder. It frequently causes neuropathies, microvascular, and macrovascular issues to appear. It is widely accepted that the health of oral tissues is correlated with the quantity and quality of saliva, both of which may be impacted by diabetes. Materials and Methods: There were 120 participants in this study, 80 of whom had Type II DM (which includes both controlled and uncontrolled diabetes), and 40 of whom did not have the disease (controls). The participants in the study, whose ages ranged from 40 to 70, comprised both sexes. Three groups were formed from the study subjects. Results: Based on the values of total protein, sodium, potassium, and salivary flow rate among controls, controlled diabetes, and uncontrolled diabetes, multiple comparisons between the groups were made using the analysis of variance and post hoc Tukey honestly significant difference analysis in version 16.0 of SPSS software. The values of total protein, sodium, potassium, and salivary flow rate among controls, controlled diabetes, and uncontrolled diabetes were gathered, formulated, and subjected to multiple comparisons between groups using analysis of variance and post hoc Tukey honestly significant difference analysis in Version 16.0 of the Statistical Package for the Social Sciences (SPSS), IBM Corporation, Chicago, United States of America. With results ranging from 79 mg/dL to 96 mg/dL, the average fasting blood sugar for Group 1 was 88.9 mg/dL. Conclusion: Studies with a larger sample size are necessary to determine the precise pathophysiology of controlled and uncontrolled Type II DM in terms of salivary flow rate, salivary electrolytes, and total protein.