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Volume 12 Issue 1 (January- March) 2023

Original Articles

Maternal and Fetal outcome in usage of magnesium sulphate for fetal neuroprotection in pregnancy less than 34 weeks of gestation
Dr. Mamatha S, Dr. Ananda M, Dr. Salma Shaziya, Dr. Manjunatha S, Dr. Somashekar HK

Magnesium is an essential component in the central nervous system and is irreplaceable in several metabolic functions in the cell, therefore occupying a key place in cell death and developmental processes. Although the effects of magnesium sulfate are not well understood, its neuroprotective properties can be explained by its anti-inflammatory and anti-excitotoxic effects. This is an observational study done in the Department of Obstetrics and Gynecology, Kodagu Intitute of Medical Sciences, Madikeri from November 2020- November 2021 involving 52 pregnant women. Mode of delivery, 14(27%) had term cesarean delivery,18(35%) had preterm vaginal delivery, 13(25%) had full term vaginal delivery and 7(13%) had preterm cesarean delivery. 96.2% had no reactions, minor reactions noted were tachycardia, blurring of vision, absent knee jerk only among 2 persons. Among 23 babies had normal birth weight,27 were born with low birth weight and 5 babies were born with very low birth weight.In our study 3 perinatal deaths occurred. 2 cases developed delay in development. 1 at 3 months and another 1 case had severe gross motor dysfunction at 6 months postnatal follow up.

 
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