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Volume 12 Issue 2 ( April- June) 2023

Original Articles

Utility of diffusion weighted imaging and apparent diffusion coefficient values in differentiating benign and malignant soft tissue tumors: A scientific article
Syed Farhanulla,Meghana RajashekaraSwamy,Sujith RajashekarSwamy,Tatiyana L.C Harris, Erin L.Myers, Sara Elsayed

Objective: This study aimed to characterize benign and malignant soft tissue tumors on MRI via diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADC) values. Materials and Methods: The investigation conducted was an observational study with cross-sectional design. The study population consisted of 30 Indian patients who presented at a tertiary care center in South India to the Department of Radiodiagnosis between November 2019 to May 2021. Study subjects were selected based on strict inclusion and exclusion criteria. They were then put through a detailed clinical assessment followed by imaging via MRI, performed using a 1.5 Tesla MRI scanner. Imaging and interpretation were performed by a team of radiologists who were unaware of the patient demographics, presentation and suggested clinical differential diagnoses. A detailed protocol utilizing various imaging techniques in multiple planes was employed. Apparent diffusion coefficient values were calculated automatically by an inbuilt software. Further methods involved drawing a fixed region of interest (ROI) over the tumor showing diffusion restriction. Preliminary imaging diagnoses were confirmed by histopathology. Results: Study data revealed a significant difference in the mean apparent diffusion coefficient values of benign and malignant soft tissue tumors. Additional information derived included frequency of certain tumor subtypes among patients and demographic characteristics relating to certain tumors. Conclusion: Results from this study support the prevailing idea that diffusion weighted imaging and apparent diffusion coefficient values are valuable supplemental tools to diagnose and manage soft tissue tumors.

 
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