Introduction: Neck masses are swellings or enlargements of the structures in the area between the inferior border of mandible and clavicle. As there are many potential causes of neck masses; it is important to proceed in logical and cost effective manner for the proper diagnosis of neck masses. Ultrasonography (B-mode, Doppler, linear probe) is a widely employed imaging modality for the study of the neck, in particular for thyroid, parathyroid, salivary glands and lymphnodes. Color Doppler allows assessment of vascularity within the lesion, e.g. in the assessment of vascular malformations, hemangiomasetc. Objectives: To identify the Sonographic and Doppler characteristics of neck masses and to assess the accuracy of high resolution ultrasound in the evaluation of neck masses after confirmation of diagnosis with fine needle aspiration cytology and histopathology follow up wherever possible. Material and Methods: this prospective observational study was conducted on a cohort of 100 patients in the Department of Radiodiagnosis and Imaging, Government Medical College, for sonographic and Doppler evaluation of the neck masses. Result: Out of 100 cases, patients with thyroid gland pathology formed the largest group (35%), followed by lymph nodes (30%), congenital and miscellaneous lesions (20%), salivary gland disease (13%) and parathyroid adenomas (2%). Maximum number of cases were seen in 21-40 years (46%) age category followed by 41-60 years (26%) with female predominance. Out of the total cases of thyroid gland pathology, 66% were diagnosed to have multinodular goiter. A significant correlation of p-value <0.05 was observed in our study between Duplex ultrasonography and FNAC/HPE resulting in good accuracy. Conclusions: Ultrasound and Color Doppleris one of the most valuable investigation tools to evaluate neck masses with respect to size, site, consistency and vascularity. It helps in distinguishing solid from cystic lesions and allows the guidance of needles accurately into the lesion of interest to obtain a diagnostic fine cytology/ biopsy