Background: The present study was conducted for assessing and comparing flexural strength in two types of denture base resins. Materials & methods: The goal of the current study was to evaluate and contrast the flexural strength of two different denture base resin types. There were 50 acrylic specimens manufactured in total using stainless steel dies. These stainless steel dies were used to create 20 acrylic specimens. To complete the flasking process, dental plaster was applied to the metal dies. For the purpose of making room in the mould for the acrylic specimen, the stainless steel dies were then removed. The following research groups were created by randomly selecting all of the specimens: 1)Conventional denture base resins fall under Group 1and glass reinforced denture base resins go under Group 2. For 28 days at room temperature, all twenty samples were submerged in distilled water to mimic the oral environment. The universal testing apparatus was used to determine the samples' flexural strength. The SPSS software was used to assess all the results, which were recorded in a Microsoft Excel spreadsheet. Results: Mean flexural strength of group 1 specimens was found to be116.9 MPa. Mean flexural strength of group 2 specimens was found to be153.6 MPa. While comparing the mean flexural strength between group 1 and group 2, statistically significant results were obtained. Conclusion: Glass reinforced denture base resins demonstrated higher flexural strength in comparison to conventional denture base resin.