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Volume 12 Issue 2 ( April- June) 2023

Original Articles

Correlation between glycosylated hemoglobin and dyslipidemia in type 2 diabetes mellitus patients
Dr. Rajesh Kumar, Dr. Navil Kumar Sharma, Dr.Vijay Vachhani, Dr. Rahul Thakur

Background: Diabetic patients with concomitant dyslipidemia are often soft targets for cardiovascular disease and deaths. An early intervention to normalize circulating lipids has been shown to reduce cardiovascular morbidity and mortality. Hence, this study aimed to determine the relationship between dyslipidemia and glycemic status in patients with type 2 DM (T2DM) patients.Material and Methods: This was a cross-sectional and prospective study was carried out at Tertiary Care Teaching Hospital over a period of 01 year. Total of 70 T2DM patients with dyslipidemia enrolled in this study. Fasting blood glucose (FBG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), triglyceride (TG) and glycosylated hemoglobin (HbA1c) levels were evaluated. Test of significance was calculated by unpaired Student’s ‘test. Correlation studies (Pearson's correlation) were performed between glycosylated hemoglobin (HbA1c) and serum lipid profile.Results: Distribution of Glucose Triad results of FBS, PPBS and HbA1c levels of patients presented as Mean± SD, mean FBS was 173.59±39.64, mean PPBS was CBYU 234.59±94.59 and mean HbA1c was 7.78±0.83. Mean total cholesterol was 226.53 ± 19.53, mean total triglyceride was 213.83 ± 20.65, Mean HDL was 35.63 ± 3.96, mean LDL was 148.14 ± 7.63 and VLDL was 42.76 ± 3.69. HbA1c positively and significantly correlated with total cholesterol (r=0.213), LDL (r=0.304), HbA1c negatively and significantly correlated with HDL (r=-0.128), and did not show any show correlation with VLDL (r=0.049) and total triglycerides (r=0.049).Conclusion: The study indicates the usefulness of HbA1c as a marker for lipid profile for screening of diabetic patients at high risk of developing cardiovascular diseases.

 
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