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Volume 12 Issue 1 (January- March) 2023

Original Articles

Assessment of cardiovascular dysfunction in chronic liver disease
Dr. Prem Narayan Vaish

Background: Cardiovascular (CV) dysfunction refers to any abnormality or impairment in the function of the cardiovascular system, which includes the heart, blood vessels, and blood. The present study was conducted to assess cardiovascular dysfunction in chronic liver disease. Materials & Methods: 68 patients of chronic liver disease of both genders were subjected to liver function test (LFT), prothrombin time/international normalized ratio (INR), abdominal ultrasound, upper gastrointestinal endoscopy, cytology and serum ascites albumin gradient, HBsAg, anti-HCV, serum ceruloplasmin, and antinuclear antibody. Child-Pugh Score was calculated to classify the severity of CLD. Parameters such as stroke volume index (SVI), cardiac index (CI), ejection fraction (EF), diastolic dysfunction (DD), left ventricular mass index (LVMI) etc. was recorded. Results: Out of 68 patients, males were 40 and females were 28. Chronic liver disease was mild in 12, moderate in 17 and severe in 39 cases. The difference was significant (P< 0.05). Stroke volume index (SVI) was increased in 38 and decreased in 30, cardiac index (CI) was increased in 42 and decreased in 26. Ejection fraction (EF) was increased in 40 and decreased in 28, diastolic dysfunction (DD) was seen in 25 and increased EF after paracentesis was seen in 14 cases. The difference was significant (P< 0.05). Conclusion: Predicting the likelihood of unfavourable cardiac events requires a high level of understanding of the presence of cirrhotic cardiomyopathy and CV dysfunction in CLD patients.

 
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