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Volume 12 Issue 2 ( April- June) 2023

Case Reports

Mucormycosis – An emerging complication in post-covid 19 patients: A case series
Dr. Shubham Varshney, Dr. Raghav Kapoor, Dr. Adarsh Sanikop

Background: Coronavirus disease 2019 (COVID-19) is the primary cause of an emergency worldwide pandemic, driven by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Immune suppression was discovered in COVID-19 patients, which was linked to injudicious use of corticosteroids and previous uncontrolled diabetes and hematological malignancies. As a result, a wide spectrum of bacterial and fungal illnesses develop.Mucormycosis is a zygomycete-related opportunistic fungal infection of the order mucorales that can cause a variety of infections1. In immunocompetent people, the fungi responsible are typically non-pathogenic since they are common environmental organisms.Based on clinical and radiological appearance, it might be difficult to tell the difference between a bacterial or fungal infection in an existing viral pneumonia3. Microbiological examination followed by histopathological confirmation add great value to diagnosis5. Objective: To evaluate mucormycosis fungal infection in rt- PCR confirmed post covid 19 patients in clinically suspected biopsies. Method: This study was conducted in Department of Pathology, KLE Hospital, Belagavi, Karnataka from April 2021 – June 2021.All medical records were reviewed and clinical details including age, sex, and predisposing conditions were obtained from the requisition forms of the patients available in the department. Post - COVID-19 patients with associated clinical suspicion of fungal infections were included in the study. Results: Our study included 100 clinically suspected of fungal infection most probably mucormycosis in post covid 19 patients.22 patients were female and 78 were male. Mean age of the case was 52 years. Out of 100 suspected mucormycosis patients, 81 biopsy specimens turned out to be positive for mucormycosis on histopathology and 19 patients as Sinusitis. Out of 100 suspected mucormycosis patients, 93 patients were immunosuppressed and 7 patients immunocompetent. Among the immunosuppressed patients, majority were having Diabetes Mellitus followed by allergic sinusitis and bronchial asthma, followed by chronic kidney disease and hematological malignancies.

 
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