1. How to submit my research paper? What’s the process of publication of my paper?
The journal receives submitted manuscripts via email only. Please submit your research paper in .doc or.pdf format to the submission email: ijlbpr@ejournal.net.
You’ll be given a paper number if your submission is successful. Your paper then will undergo peer review process, which may take approximately one and a half months under normal circumstances, three tops.
After blind peer review, you will receive the notification letter with the review result of your paper...
2. Can I submit an abstract?
The journal publishes full research papers. So only full paper submission should be [Read More]

Production of PHA by Recombinant Organisms

M Thirumala1 and S Vishnuvardhan Reddy2
1 Department of Biochemistry, Mahatma Gandhi University, Nalgonda - 508254, AP, India.
2 Department of Plant Sciences, University of Hyderabad, Hyderabad - 500046, AP, India.
Abstract—Polyhydroxyalkanoates (PHA) are biodegradable, thermoplastic polyesters produced from renewable carbon sources by a number of bacteria. However, their application is limited by high production costs. One of the strategies aimed to reduce their costs is the development of recombinant strains able to utilize different carbon sources. Many bacteria are naturally capable of accumulating biopolyesters composed of 3-hydroxy fatty acids as intracellular inclusions, which serve as storage granules. Recently, these inclusions have been considered as nano/ microbeads with surface-attached proteins, which can be engineered to display various protein- based functions that are suitable for biotechnological and biomedical applications. Natural PHA producers have become accustomed to accumulating PHA during evolution; they often have a long generation time, relatively low optimal growth temperature, are often hard to lysis and contain pathways for PHA degradation. This led to the development of recombinant PHA producers, capable of high PHA accumulation and/or free of PHA degradative pathways. This review summarizes the production of PHA by recombinant bacteria as well as some higher organisms in brief.

Index Terms—Polyhydroxyalkanoates, Production, Recombinant bacteria

Cite: M Thirumala and S Vishnuvardhan Reddy, " Oral Micro-Particulate Colon Targeted Drug Delivery System for the Treatment of Crohns Disease: A Review," International Journal of Life Sciences Biotechnology and Pharma Research, Vol. 1, No. 2, pp. 40-62, April 2012.
Copyright © 2012-2015 International Journal of Life Sciences Biotechnology and Pharma Research, All Rights Reserved