Review on Cancer Stem Cells - Volume 2, No.1, January, 2013 - IJLBPR
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Review on Cancer Stem Cells

Shahrzad Saeidpour and Maryam Torabizadeh
Department of biotechnology, Jawaharlal Nehru Technological University, India.
Abstract—Cancer is one of the leading causes of death in the developed, developing as well as undeveloped nations in the world. Cancer is caused due to loss of function of cell cycle check point factors that leads to uncontrolled proliferation of cells. Often cancer originates in a particular tissue but cancer cells migrate to distant tissues by a phenomenon known as metastasis. The invasiveness properties of cancerous cells are often exhibited by the Cancer Stem Cells (CSCs), which possess similar properties as that of normal stem cells such as self renewal ability and differentiation capacity depending upon the tissue-specific occurrence. CSCs are often not destroyed with most of the cancer preventing therapeutics and thus they metastasize to different tissues and cause cancer recurrence. Currently available therapeutics for cancer is targeting only cancerous cells and failed to kill the CSCs which plays a major role in tumorigenicity there by leading to recurrence of cancer.

Index Terms—Cancer, Cancer Stem Cells, Anti-Cancer Drug

Cite: Shahrzad Saeidpour and Maryam Torabizadeh, "Review on Cancer Stem Cells," International Journal of Life Sciences Biotechnology and Pharma Research, Vol. 2, No. 1, pp. 30-37, January 2013.
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