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The journal receives submitted manuscripts via email only. Please submit your research paper in .doc or.pdf format to the submission email: ijlbpr@ejournal.net.
You’ll be given a paper number if your submission is successful. Your paper then will undergo peer review process, which may take approximately one and a half months under normal circumstances, three tops.
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The journal publishes full research papers. So only full paper submission should be [Read More]

Haematological and Cytotoxic Effect of the Ethanolic Extract of Vitex Negundo

N. Kannikaparameswari and T. Indhumathi
Postgraduate and Research Department of Biochemistry, Dr.N.G.P.Arts and Science College, Coimbatore-48.
Abstract—Cancer is a class of disease in which a group of cells display uncontrolled growth, invasion and sometimes metastasis. These three malignant properties of cancers differentiate from benign tumors, which are self-limited and do not invade or metastasis. Most cancers form a tumor but some, like leukemia, do not. Cancer may affect all ages. Even fetuses but the risk for most varieties increases with ages Cancer is a major public health burden in both developed and developing countries. The areas of cancer and infectious diseases have a leading position in utilization of medicinal plants as a source of drug discovery. Among FDA approved anticancer and anti-infectious preparations drugs of natural origin have a share of 60% and 75% respectively. So the present study was designed to analyze the anti-cancer potential of the Vitex negundo extract against Ehrlich¡¯s Ascite Carcinoma (EAC) Cell line (In vivo).The ethanolic extract of Vitex negundo extract treatment showed decrease in tumor volume, packed cell volume and viable cell count and increases the nonviable cell count and mean survival time (MST), thereby increasing life span of EAC tumor bearing mice. Hematological profile reverted to more (or) less normal levels in extract treated mice. The data presented here clearly encourage the development of Vitex negundo for chemopreventive agent.

Index Terms—Vitex negundo, Chemoprevention

Cite: N. Kannikaparameswari and T. Indhumathi, "Haematological and Cytotoxic Effect of the Ethanolic Extract of Vitex Negundo," International Journal of Life Sciences Biotechnology and Pharma Research, Vol. 2, No. 1, pp. 247-253, January 2013.
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