Flow-Injection Chemiluminescence Determination of Glucose Using Potassium Permanganate-Luminol CL System - Volume 2, No.4, October, 2013 - IJLBPR
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Flow-Injection Chemiluminescence Determination of Glucose Using Potassium Permanganate-Luminol CL System

Zoumana Sekou Traore 1, Xingguang Su 2, Moussa Tamboura 3, and Anna M Mikhailova 3
1. University of Sciences, Techniques and Technology of Bamako, Sciences and Techniques Faculty Department of Chemistry
2. Department of Analytical Chemistry, College of Chemistry, Jilin University, Changchun130012, China
3. University of Sciences, Techniques and Technology of Bamako, Sciences and Techniques Faculty Department of Chemistry
Abstract—A new flow-injection chemiluminescence method was developed for the determination of glucose in physiologic liquids, which was based on the enhancement effect of glucose on the chemiluminescence signal generated by KMnO4-luminol system in alkaline medium. Under optimized conditions, a linear correlation was established between the chemiluminescence intensity and the glucose concentration in the range of 7.2×10–5 to 2.3×10–8 M with a detection limit (3σ) of 1.2×10–9 M. The relative standard deviation for 11 measurements is 2.12%. The method was applied to determine the glucose concentration in the human serum samples and the results are consistent with those obtained by the standard spectrometric method. 

Index Terms—flow-injection, chemiluminescence, blood serum glucose

Cite: Zoumana Sekou Traore, Xingguang Su, Moussa Tamboura, and Anna M Mikhailova, "Flow-Injection Chemiluminescence Determination of Glucose Using Potassium Permanganate-Luminol CL System," International Journal of Life Sciences Biotechnology and Pharma Research, Vol. 2, No. 4, pp. 52-63, October 2013.
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