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Pattern of Total White Blood Cell and Differential Count Values in HIV Positive Patients Receiving Treatment in Federal Teaching Hospital Abakaliki, Ebonyi State, Nigeria

Obeagu Emmanuel Ifeanyi1, Obarezi Thompson Ndubuisi1, Ogbuabor Bernice Nwakaego2, Anaebo Queen Braxton N3, and Eze Godwin Chidolue4
1. Diagnostic Laboratory Unit, University Health Services Department, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria
2. Department of Medical Laboratory Science, ESUT Teaching Hospital, Enugu State, Nigeria
3. Medical Doctor, Department of Accident and Emergency, Lagos State University Teaching Hospital, Nigeria
4. White Chapel Specialist Hospital, No. 12 Uzodimma Street, Fegge Onitsha, Anambra State, Nigeria
Abstract—The assessment of values of differential counts was carried out on one hundred (100) samples. Sixty (60) samples (test) were collected from HIV positive patients who came for routine medical check up and treatment at Federal Teaching Hospital Abakaliki and forty (40) samples (control) were from HIV negative individuals who were voluntary blood donors at the same hospital. The subjects were age matched from 16-65 years. 34% of the subjects were 16-25 years. 41% of the subjects were 26-35 years and 25% of the subjects were 36-45 years. The total white blood cell count result for HIV positive patients were 2.8*109/l (16-25 years), 2.9*109/l (26-35 years), 3.2*109/l (36-45 years) which were lower than mean values of HIV negative subjects as follows 6.4*109/l (16-25 years), 6.5*109/l (26-35 years) and 7.0*109/l (36-45 years). This showed significant difference in the mean values of total white blood cell of the HIV positive patients and HIV negative subjects (p<0.05). Mean differential white blood cell count of HIV positive patients were 16-25 years (Neutrophil 58.1%, Lymphocyte 37.5%, Monocyte 1.9%. Eosinophil 2.7% and Basophil 0.3%), 26-35 years (Neutrophil 55.1%, Lymphocyte 39.5%, Monocyte 2.6%, Eosinophil 2.6% and Basophil 0.3%) and 36-45 years (Neutrophil 57.4%, Lymphocyte 38%, Monocyte 2.3%, Eosinophil 1.8% and Basophil 0.2%). The differential count of HIV negative subjects were 16-25 years (Neutrophil 58.8%, Lymphocyte 30.2%, Monocyte 2.1%, Eosinophil 1.5% and Basophil 0.4%), 26-35 years (Neutrophil 61.1%, Lymphocyte 35.4%, Monocyte 2.0%, Eosinophil 1.3% and Basophil 0.2%) and 36-45 years (Neutrophil 56.4%, Lymphocyte 36.4%, Monocyte 3.4%, Eosinophil 1.4% and Basophil 0%). This showed no significant difference in the differential count. 

Index Terms—HIV, basophil, neutrophil, lymphocyte, eosinophil, monocyte, positive and negative, patients

Cite: Obeagu Emmanuel Ifeanyi, Obarezi Thompson Ndubuisi, Ogbuabor Bernice Nwakaego, Anaebo Queen Braxton N, and Eze Godwin Chidolue, "Pattern of Total White Blood Cell and Differential Count Values in HIV Positive Patients Receiving Treatment in Federal Teaching Hospital Abakaliki, Ebonyi State, Nigeria," International Journal of Life Sciences Biotechnology and Pharma Research, Vol. 3, No. 1, pp. 186-189, January 2014.
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