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Fine Needle Aspiration Cytology: A Diagnostic Tool in Lymphadenopthy

Mahesh S Patil1 and Anand A S2
1. Department of Pathology, BKL Walawalkar Rural Medical College and Hospital, Dervan
2. Department of Pathology, Navodaya Medical College, Raichur
Abstract—Background: Fine Needle Aspiration Cytology (FNAC) is a well accepted diagnostic procedure and considered to be a valuable test for initial assessment of lymph node swellings in all age groups (Agarwal etal., 2010). The technique has gained popularity over the last decade, with varying degrees of acceptance rates, accuracy, and results among pathologists. Objectives: To evaluate the utility of aspiration cytology as a first-line diagnostic tool in palpable lymph node lesions, in comparison to result of histopathology. Materials and methods: The present study was conducted in 252 patients presenting with Lymphadenopathy over a period of 3 years. Results: In this series of FNAC, cervical lymph nodes were 168 (66.7%), and axillary lymph nodes were 27 (10.7%). Male to female ratio of the patients were 1.3: 1.0. FNAC diagnosis was found to be as follows: reactive hyperplasia 108 (42.80%), tubercular lymphadenitis 81 (32.14%), suppurative lymphadenitis10 (3.96%). In the malignant category, metastatic deposits often involving the LN accounts to 39 (15.5%) and lymphomas 7 (2.71%) out of which 5 were Hodgkin’s and 2 were found to be Non Hodgkin’s lymphoma.34 out of 36 cases diagnosed cytologically, had good histopathological correlation. Conclusion: FNAC is a reliable, safe, accurate, sensitive and minimally invasive first-line investigation in the diagnosis of lymph node lesions. It is highly accurate in isolating and determining potentially neoplastic lesions. 

Index Terms—lymphadenopathy, FNAC, fine needle aspiration cytology, lymph nodes

Cite: Mahesh S Patil and Anand A S, "Fine Needle Aspiration Cytology: A Diagnostic Tool in Lymphadenopthy," International Journal of Life Sciences Biotechnology and Pharma Research, Vol. 3, No. 1, pp. 286-291, January 2014.
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