1. How to submit my research paper? What’s the process of publication of my paper?
The journal receives submitted manuscripts via email only. Please submit your research paper in .doc or.pdf format to the submission email: ijlbpr@ejournal.net.
You’ll be given a paper number if your submission is successful. Your paper then will undergo peer review process, which may take approximately one and a half months under normal circumstances, three tops.
After blind peer review, you will receive the notification letter with the review result of your paper...
2. Can I submit an abstract?
The journal publishes full research papers. So only full paper submission should be [Read More]

In Vitro Inhibition of MAO-A and PLA Enzymes and Antioxidant Activity of Important Medicinal Plants Extracts

Kavitha Sagar
Botanical Garden, Department of Forestry and Environmental Sciences, University of Agricultural Sciences, Gandhi Krishi Vigyan Kendra, Bengaluru
Abstract—To evaluate antioxidant and in vitro inhibition of MAO-A and PLA enzymes of medicinal plant extracts, the anti-oxidant assay was done by the following four different radical scavenging, viz., DPPH, Super oxide, Hydroxyl radical and reducing power. Amla extract showed the highest radical scavenging activity IC50 = 6 µg/mL value and the other two Gardenia IC50 = 9 µg/ mL and Blueberry IC50 = 13 µg/mL exhibited similar activity. The PLA enzyme inhibitory assay was carried out and the Blueberry and Gardenia extract showed the highest IC50 = 46 µg/mL and 38 µg/mL, respectively but less activity was observed in Amla extract. The MAO-A (monoamino oxidase) enzyme inhibitory assay was done and Blueberry and Gardenia extract inhibited this enzyme greatly when compared to Amla IC50 = 140 µg/mL, 116 µg/ml and 90 µg/mL, respectively. The present investigation evidences that all the three plant extracts exhibited significant antioxidant activity. Amla and Gardenia were found to be good inhibitors of PLA and MAO-A enzymes which are involved in anti-inflammatory and depression, respectively. 

Index Terms—anti-oxidant, medicinal plant, MAO-A, PLA

Cite: Kavitha Sagar, "In Vitro Inhibition of MAO-A and PLA Enzymes and Antioxidant Activity of Important Medicinal Plants Extracts," International Journal of Life Sciences Biotechnology and Pharma Research, Vol. 3, No. 4, pp. 40-48, October 2014.
Copyright © 2012-2015 International Journal of Life Sciences Biotechnology and Pharma Research, All Rights Reserved